Abstracts: the article presents the results of study revealing new biomarkers and neuropsychiatric disorders in patients with leukemia.
The purpose of the article is to establish the effect of bone marrow worms and neuropsychiatric disorders on the severity of leukemia. In patients with acute and chronic leukemia, mixed invasion of antibodies to Toxocara canis and Ascaris lumbricoides was detected both in the blood serum and in the bone marrow in the same patients, antibodies only to Ascaris lumbricoides in the blood serum and bone marrow were detected in almost 2,5 times less in relation to mixed invasion. In acute leukemia, the coprogram contained 3,3 times more eggs of Ascaris lumbricoides in relation to individuals of Ascaris lumbricoides, while in patients with chronic leukemia, there were no statistically significant differences between these indicators. In patients with leukemia associated with helminthic invasion, hyperplastic, anemic, hemorrhagic, intoxication, immunodeficiency syndromes, as well as neuropsychiatric disorders were more expressed than the patients with leukemia without the association of helminthic invasion. Nematodes and neuropsychiatric disorders of leukemia undoubtedly affect the severity of the disease.
Keywords: leukemia, biomarkers, helminths, toxocara, ascaris