Abstract: connective tissue dysplasia is one of the most important medical and social problems of congenital pathology in connection with progredient course, multiple organ failure and often unfavorable outcome. A total of 209 children aged 7 to 17 years of age in the schools of Khanty-Mansiysk were examined. An objective study included the recording of anthropometric indices, the stigma of disembryogenesis and small anomalies of development. All the individuals studied were natives of the northern region in the 1st and 2nd generation. The most common epicanthus and its remnants, blue scleras, funnel-shaped chest, clinodactyly, flat feet, sandal-shaped cleft, hyperelasticity of the skin, multiple moles.
Differences in the qualitative, quantitative and intersexual prevalence of signs of dysplasia in this study can be explained by age features. The greater number of signs of dysplasia during adulthood is explained by the transition of functional disorders to structural ones when the volume of socialized loads (reading, working with computers, physical culture and sports) increases among schoolchildren and students. It is necessary to monitor children with undifferentiated dysplasia dynamically to prevent nosology associated with both hereditary connective tissue failure and climatic complications.
Keywords: undifferentiated connective tissue dysplasia, children’s age, northern region