Abstract: in an experiment on 10 outbred dogs, the dynamics of intraluminal pressure in the ileum and colon was studied when modeling obstruction of the ureter on the right. In series I, in 5 animals, during the surgical intervention, the right ureter was extracted from the surrounding tissues without modeling its obstruction.
In the series II, in 5 animals, the right ureter was extracted from surrounding tissues during the operation and doped with catgut thread No. 1 at the border of the middle and lower third, thereby simulating its obstruction due to impaired patency during external clamping with a ligature. Before the operation to simulate obstruction of the right ureter, and then within 4 days after its completion, we measured the intraluminal pressure in the ileum and colon. The interval of studies for 4 days was due to the fact that after the onset of an attack of renal colic, and then admission and observation in the hospital, it took from 3 to 5 days from the onset of the attack. The pressure in the lumen of the ileum and colon was produced by the open method using the Waldman apparatus. It was established that, against the background of modeling obstruction of the right ureter in the series II of the experiment, after 1 day the indices of the intraluminal pressure in the ileum significantly exceeded the indices before the operation (P <0.05). Moreover, in the subsequent periods of the study, there was a steady tendency towards an intensive increase in intraluminal hypertension, and, accordingly, an increase in the significance of differences with indicators before surgery (P <0.05).
Thus, against the background of obstruction of the right ureter, a uretero-ileocecal inhibitory reflex develops, the implementation of which leads to dysfunction of evacuation from the ileum to the colon, which increases the risk of postoperative complications. It is pathogenetically justified to carry out prophylaxis and correction of ileocecal angle dysfunction in case of obstruction of the right ureter.
Keywords: ureter obstruction, intraluminal pressure, ileum chyme passage, ilecal angle, transurethral lithotripsy. Uretero-ileocecal reflex