Abstract: together with the acinar structures of the pancreas formed by cells in the secretion phase, single cells of the intracellular ducts are determined, containing two rounded basophilic nuclei that are surrounded by basophilic cytoplasm. These features of the cell structure correspond to the state of mitosis, which indicates the manifestations of regenerative activity of the gland cells of rats from the control group of stress-resistant animals. On histological preparations of pancreatic tissue of rats from the experimental group of stress-resistant animals withdrawn in the experiment after stress exposure, necrobiotic changes of a diffuse nature were invented. Thus, among the cells of the insular apparatus of the gland, cells with a wrinkled dark basophilic nucleus are found, located in the cytoplasm with optically empty vacuoles. Morphological changes demonstrate the phenomenon colliquation focal cell necrosis with partial destruction of their outer membrane. The cells were mainly located in the peripheral part of the Langerhans islet. There are also cells with a partially lysed nucleus. Consequently, these changes in the morphological structure of cells that are part of the insular gland apparatus indicate partially reversible and irreversible changes in the tissue of the animal organ under the damaging influence of a stress factor.
Keywords: cells, morphological structure, organs, membrane, tissues