Abstract: the theoretical justification of the reflex effect of pathological impulsation after operations on the organs of the chest cavity, retroperitoneal space and lumbar spine on the motor and evacuation function of the intestine is carried out. 2 series of experimental studies were conducted to study the effect of obstruction of the right ureter on the functional state of the intestine. In series I, 5 animals underwent surgery without modeling obstruction of the right ureter. In series II, in 5 animals, during the simulation on the border of the middle and lower third of the right ureter, the patency of the right ureter and the development of intraluminal hypertension in the pyelocaliceal system of the right kidney and ureters above the obstruction zone were modeled. The criteria for evaluation were the results of a phonoenterographic study for o, which was performed before the operation and its peristaltic assessment of the intestine within 3 days after the operation in the morning on an empty stomach, with the definition of an individual standard. It was established that against the background of obstruction of the right ureter, a pathological uretero-enteric inhibitory reflex developed, a focus of pathological impulse appeared in the retroperitoneal space on the right, leading to reflex inhibition of intestinal peristaltic activity. This is confirmed by a significant decrease in both the amplitude (P <0.05) and the number (P <0.05) of peristaltic waves in the second series of the experiment. The pathogenetic feasibility of developing measures to correct the digestive tract dysfunction after operations on the heart, lumbar spine, retroperitoneal organs and small pelvis is substantiated.
Keywords: uretero-cardial reflex, intestinal dysfunction, intestinal motility, retroperitoneal space, pyelocaliceal hypertension