Abstract: the clinic conducted research aimed at identifying local endogenous intoxication in 135 patients with bacterial vaginosis before treatment and depending on its dynamics, taking into account the effectiveness of the treatment. All patients considered in this work gave written informed consent and signed a bilateral agreement on non-disclosure of personal data. Diagnosis and treatment was carried out in accordance with the protocols of the Republic of Kazakhstan. Criteria for analysis were indicators of residual nitrogen, nitrogen-containing compounds and coefficient of CASS / OA, reflecting the ratio of ACC in the structure of OA in the vaginal secretion before the start of treatment and after 7 and 30 days after the end of treatment. It was found that the content of residual nitrogen, nitrogen-containing compounds and the coefficient of CASS / OA, reflecting the ratio of ACC in the structure of OA in vaginal secretion, regardless of the effectiveness of the treatment, after 7 days was significantly reduced. However, 30 days after treatment with the number of key cells in the material from the vagina more than 3% residual nitrogen, nitrogen-containing compounds and the coefficient CASS / OA, reflecting the ratio of ACC in the structure of the OA in vaginal secretion somewhat exceeded the figures before the start of treatment, but the differences were unreliable P> 0.05). It is advisable to continue research in this direction.
Keywords: vaginosis, nitrogen-containing compounds, residual nitrogen, key cells, local endogenous intoxication