{"id":8939,"date":"2019-05-20T16:37:07","date_gmt":"2019-05-20T13:37:07","guid":{"rendered":"http:\/\/ijmp.ru\/?p=8939"},"modified":"2019-06-28T13:51:07","modified_gmt":"2019-06-28T10:51:07","slug":"osobennosti-klinicheskogo-techenija-pnevmocistnoj-pnevmonii-u-vich-inficirovannyh-bolnyh","status":"publish","type":"post","link":"https:\/\/ijmp.ru\/en\/archives\/8939","title":{"rendered":"CLINICAL FEATURES PNEUMOCYSTIS IN HIV-INFECTED PATIENTS"},"content":{"rendered":"<p><strong>Abstract:<\/strong> one of the first symptoms allowing to suspect an immune deficiency is pneumonia. The most common in HIV-infected patients is pneumocyst pneumonia.<\/p>\n<p>The aim of the investigation was to study the clinical course of pneumocyst pneumonia in HIV-infected patients.<\/p>\n<p>Materials and methods: the analysis of literature data and retrospective analysis of 143 case histories of deceased patients admitted to the hospital of GO BUZ &#8220;Novgorod regional infectious diseases hospital&#8221; for the period from 2004 to 2016. The study included patients with different stages of the disease, with previously known HIV status for the first time revealed patients. Socio-demographic, clinical (AIDS-indicator and related diseases), as well as immunological characteristics were taken into account.<\/p>\n<p>Conclusion: verification of the diagnosis of pneumocyst pneumonia is based on the identification of a characteristic clinical picture (leading syndrome \u2014 progressive respiratory failure); determining the immunodeficiency status of the patient; high rates of ESR and total LDH activity, arterial hypoxemia (decrease in Rao2); isolation of the causative agent from the biological material of the respiratory tract; radiological and bilateral interstitial infiltrative changes in the lungs.<\/p>\n<p>To prevent the development of pneumocystic pneumonia, it is necessary to increase the number of HIV tests in vulnerable groups (to reduce the frequency of late-onset patients), increase the number of patients who are on dispensary supervision, timely prevent pneumonia of HIV-infected patients (with a decrease in SD4-lymphocytes &lt;200 with Biseptol), as well as timely prescribe and use art as prevention.<\/p>\n<p><strong>Keywords:<\/strong> HIV infection, Pneumocystis penumonia, opportunistic infections, clinical features, diagnosis, CD4-lymphocytes<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Abstract: one of the first symptoms allowing to suspect an immune deficiency is pneumonia. The most common in HIV-infected patients is pneumocyst pneumonia. The aim of the investigation was to study the clinical course of pneumocyst pneumonia in HIV-infected patients. Materials and methods: the analysis of literature data and retrospective analysis of 143 case histories [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[18,19],"tags":[41,42,43],"class_list":["post-8939","post","type-post","status-publish","format-standard","hentry","category-2018g","category-tom-1-1","tag-azovceva-o-v","tag-bogachjova-t-e","tag-semjonova-o-d"],"translation":{"provider":"WPGlobus","version":"3.0.0","language":"en","enabled_languages":["ru","en"],"languages":{"ru":{"title":true,"content":true,"excerpt":false},"en":{"title":true,"content":true,"excerpt":false}}},"_links":{"self":[{"href":"https:\/\/ijmp.ru\/en\/wp-json\/wp\/v2\/posts\/8939","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/ijmp.ru\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/ijmp.ru\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/ijmp.ru\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/ijmp.ru\/en\/wp-json\/wp\/v2\/comments?post=8939"}],"version-history":[{"count":3,"href":"https:\/\/ijmp.ru\/en\/wp-json\/wp\/v2\/posts\/8939\/revisions"}],"predecessor-version":[{"id":9141,"href":"https:\/\/ijmp.ru\/en\/wp-json\/wp\/v2\/posts\/8939\/revisions\/9141"}],"wp:attachment":[{"href":"https:\/\/ijmp.ru\/en\/wp-json\/wp\/v2\/media?parent=8939"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/ijmp.ru\/en\/wp-json\/wp\/v2\/categories?post=8939"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/ijmp.ru\/en\/wp-json\/wp\/v2\/tags?post=8939"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}